Long-term follow-up of dogs with leishmaniosis treated with meglumine antimoniate plus allopurinol versus miltefosine plus allopurinol
نویسندگان
چکیده
منابع مشابه
Treatment of cutaneous leishmaniasis with combination of allopurinol and low dose of meglumine antimoniate
cutaneous leishmaniasis is one of the most prevalent endemic disease in Isfahan which is also hyperendemic in other parts of Iran.different treatment have been suddested for cutaneous Ieihmaniasis is glucantim and pentostam,however these drugs have significant side effects and can only be used intravenously.allopurinol is one of the oral medicines suggested for the treatment of cutaneous leishm...
متن کاملClinical, serologic, and parasitologic follow-up after long-term allopurinol therapy of dogs naturally infected with Leishmania infantum.
Canine leishmaniasis usually is treated with antimony compounds, but frequent relapses, adverse effects, high costs, and development of resistance to long-term antimonial therapy emphasize the importance of searching for alternative antileishmanial drugs. Allopurinol was used at a dosage of 10 mg/kg/day PO to treat 10 dogs naturally infected with Leishmania infantum for a period of 2-24 months....
متن کاملSuccessful treatment of feline leishmaniosis using a combination of allopurinol and N-methyl-glucamine antimoniate
CASE SUMMARY This work describes the diagnosis and successful treatment of a 2-year-old domestic cat infected with Leishmania species and presenting fever, and ulcerative and nodular skin lesions after being treated for pyodermatitis for 1 year without clinical improvement. After anamnesis the cat was submitted to a complete clinical examination. Blood was collected for determination of haemato...
متن کاملProteinuria reduction after treatment with miltefosine and allopurinol in dogs naturally infected with leishmaniasis
AIM The aim of this study was to evaluate changes in proteinuria in dogs naturally infected with visceral leishmaniasis, following treatment with miltefosine (MLF) and allopurinol. MATERIALS AND METHODS Medical records of 40 dogs with leishmaniasis, treated with 2 mg/kg MLF every 24 h PO and 10 mg/kg allopurinol every 12 h for 28 days were reviewed. 20 dogs were included in the study, and cli...
متن کاملEvaluation of a Possible Synergistic Effect of Meglumine Antimoniate with Paromomycin, Miltefosine or Allopurinol on in Vitro Susceptibility of Leishmania tropica Resistant Isolate
BACKGROUND Pentavalent antimonials are still the first choice treatment for leishmaniasis, but with low efficacy and resistance is emerging. In the present study, the effect of meglumine antimoniate (MA, Glucantime) combined with paromomycin, miltefosine or allopurinol on in vitro susceptibility of Leishmania tropica resistant isolate was evaluated. METHOD The drugs were obtained from commerc...
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ژورنال
عنوان ژورنال: Parasites & Vectors
سال: 2015
ISSN: 1756-3305
DOI: 10.1186/s13071-015-0896-0